Leptin Resistance and Weight Loss

LEPTIN RESISTANCE and WEIGHT LOSS

Venus Factor’s presentation talks a lot about the Leptin hormone. (watch the video here)

So What Does Leptin really do?

The Leptin hormone is related to controlling our weight. Leptin’s interesting job is to report to your brain that your body has adequate energy and that the body has had enough to eat.

So obviously we ALL want a good supply of Leptin in our bodies.

We all have Leptin in our bodies ...... enough of it to be able to do it's job of weight control. Even overweight people have adequate Leptin in their bodies; so why are they over weight?

The answer is Leptin resistance. This area is a little complicated and sketchy, but it is an important subject.

For some reason it appears that in some people the receptors for Leptin are working poorly or only working on a limited basis. Research has shown that many other factors influence how well or poorly the Leptin’s message is getting through.

This resistance is sometimes described as a metabolic disorder that contributes to obesity, similar to the way insulin resistance is sometimes described as a metabolic disorder that has the potential to progress into type 2 diabetes, however it is not certain that this is true for Leptin in most cases.
 
The mere fact that Leptin resistance is extremely common in obese individuals suggests it may simply be an adaptation to excess body weight.

It is suspected that the major physiological role of Leptin is not to act as a “satiety signal” to prevent obesity in times of stored energy excess, but as a “starvation signal” to maintain adequate fat stores for survival during times of energy deficit.

So Leptin resistance in overweight individuals is a standard feature of mammalian physiology in general, which possibly confers a survival advantage. This evolutionary advantage: “the ability to efficiently store energy during periods of sporadic feast", represented a survival advantage in ancestral societies subjected to periods of starvation.

So it could be the combination of two mechanisms (one, which temporarily suspends Leptin action when presented with an excess of high-quality food, and the other, which blunts the processes that could drive the body weight back to “normal”), that explains the current obesity epidemic rather than it being the invoking of a metabolic disorder or a combination of “villain” nutrients.

So What Diet Factors Are The Possible Cause?

In rats, it was discovered that fructose, greatly inhibited Leptin reception. Normally when rats are given Leptin injections, they eat less. However when given a diet of 60% fructose and Leptin injections, the Leptin didn't seem to have the desired effect. The rats were still hungry. This is why it is important for you to avoid fructose, and probably many other additives.

So What Does This Mean?

It is not a question of getting more Leptin, but rather utilizing the Leptin you do have. If your receptors are not making use of the Leptin you will remain hungry and probably stay overweight. That is why it is so crucial to avoid fructose and other food additives.

Venus Factor allows you to utilize your existing Leptin to the maximum effect. This is "basically" what Venus Factor is all about. Not starvation dieting; just staying away from obvious "bad influences" in the food world.

Final word:

If this small introduction to Leptin has become a fascinating interest to you it might be of great benefit to read a book called “Mastering Leptin”. It is available on Amazon.com as a paper back book (there is also a kindle digital version available).